Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 2,160 | 待询 | ||
10 mg | ¥ 3,860 | 待询 | ||
50 mg | ¥ 11,510 | 待询 | ||
100 mg | ¥ 17,885 | 待询 | ||
200 mg | 待询 | 待询 | ||
500 mg | 待询 | 待询 |
产品描述 | AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide. |
体外活性 | AT-1002 reversibly increases the paracellular transport of molecules across the epithelial barrier. AT-1002 can undergo Cys-Cys dimerization [1]. Undifferentiated Caco-2 cells are treated with AT-1002 (0 to 5 mg/mL, 3 or 24 hours) and viability is assessed by measuring cellular ATP content. Treatment with AT-1002 for up to 3 h does not affect cell viability at any concentration. In particular, the viability of Caco-2 cells is not affected by 5 mg/mL AT-1002. AT-1002 reduces cell viability after 24 h at concentrations of 2.5 mg/mL and higher. However, the cells remain viable after 24 h if the cells are washed after exposure to AT-1002 for 3 h [2]. |
别名 | AT-1002 TFA |
分子量 | 821.91 |
分子式 | C34H54F3N9O9S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
AT-1002 TFA (835872-35-0 free base) Others AT1002 TFA (835872350 free base) 835872-35-0 free base AT-1002 TFA AT 1002 TFA (835872 35 0 free base) 835872-35-0 Inhibitor inhibitor inhibit